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Generic Mevacor - Lovastatin is an antilipemic agent produced by fermentation of Aspergillus terreus, is the first of a class of lipid-lowering agents known as the HMG-CoA reductase inhibitors. Generic Mevacor - Lovastatin is a lactone that is readily hydrolyzed in vivo to the corresponding b-hydroxyacid, a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate. The conversion of HMG-CoA to mevalonate is an early step in the biosynthetic pathway for cholesterol.
Active Ingredient: Lovastatin
Inactive Ingredients: inactive ingredients: cellulose, lactose, magnesium stearate, and starch. Butylated hydroxyanisole (BHA) is added as a preservative. Tablets MEVACOR 20 mg also contain FD&C Blue 2.

Generic Mevacor - Lovastatin is used to treat hypercholesterolemia, to slow coronary atherosclerosis, and to prevent myocardial infarction and stroke. Generic Mevacor - Lovastatin is a prodrug, concentrating active drug in the liver during first-pass circulation. For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia; For primary prevention of coronary heart disease.

Take Generic Mevacor - Lovastatin tablets by mouth. Follow the directions on the prescription label. Take Generic Mevacor - Lovastatin tablets with food. If you take Generic Mevacor - Lovastatin once a day, take the dose with the evening meal. Swallow the tablets with a drink of water. Do not take Generic Mevacor - Lovastatin with grapefruit juice; orange juice may be used instead. Take your doses at regular intervals. Do not take your medicine more often than directed. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.
STORAGE
Store at room temperature away from excess heat and moisture (not in the bathroom) and light. Keep all medicines away from children and pets. Throw away any medication that is outdated or no longer needed.

Do not take Generic Mevacor - Lovastatin if you are sensitive to or have ever had an allergic reaction to Generic Mevacor (Lovastatin) or similar anticholesterol drugs.

Do not take Generic Mevacor - Lovastatin if you are being treated for any disease that contributes to increased blood cholesterol, such as hypothyroidism, diabetes, nephritic syndrome (kidney and blood vessel disorder), dysproteinemia (an excess of protein in the blood), or liver disease, your doctor will closely monitor your reaction to Generic Mevacor (Lovastatin).

Do not take Generic Mevacor - Lovastatin if you are planning to have elective surgery, Generic Mevacor (Lovastatin) should be discontinued a few days before the operation.

Do not take do not take Generic Mevacor - Lovastatin if you are being treated for liver disease.

Do not take Generic Mevacor - Lovastatin if you are pregnant or breast-feeding.

.Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one

There have been no reported cases of overdose with Generic Mevacor - Lovastatin. In case of overdoseis suspected , call emergency or your local poison control center.

Generic Mevacor - Lovastatin is usually well tolerated. Generic Mevacor - Lovastatin can rarely cause myopathy or rhabdomyolysis. Minor side effects include constipation, diarrhea, gas, heartburn, headache, and insomnia. Major side effects include abdominal pain or cramps, blurred vision, dizziness, itching, muscle pain or cramps, rash, yellowing of the skin or eyes.

Generic Mevacor - Lovastatin is generally well- tolerated by most patients. It tends to enhance the blood-thinning effect of Coumadin. In rare instances, it can also cause muscle pain and potential kidney damage when combined with the following:
• Amiodarone (Cordarone)
• Clarithromycin (Biaxin)
• Clofibrate (Atromid-S)
• Cyclosporine (Sandimmune, Neoral)
• Erythromycin (E.E.S., PCE, others)
• Fenofibrate (Tricor)
• Fluconazole (DiFlucan)
• Gemfibrozil (Lopid)
• Itraconazole (Sporanox)
• Ketoconazole (Nizoral)
• Nefazodone (Serzone)
• Nicotinic acid or niacin (Niaspan)
• Protease inhibitors (a type of drug for HIV) such as Agenerase, Crixivan, Fortovase,
• Invirase, Norvir, and Viracept
• Verapamil (Calan)

If you are taking Generic Mevacor - Lovastatin with any of these drugs, (or with large quantities of grapefruit juice), alert your doctor immediately at the first sign of muscle pain, tenderness, or weakness, especially if accompanied by fever or general body discomfort. If you need to take erythromycin, Biaxin, Nizoral, or Sporanox, the doctor may temporarily take you off Generic Mevacor - Lovastatin.

Generic Mevacor - Lovastatin is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol levels under control. It's important to remember that Mevacor is a supplement--not a substitute--for these other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor.